Jean Schlumberger started working as a button designer for Elsa Schiaperelli. She was the woman who encouraged him to design jewelry for her collections. After World War II, Jean Schlumberger moved to New York to design clothing for Chez Ninon. In 1946, he opened his jewelry salon.
His client list included Greta Garbo, John F Kennedy, Princess Marina, Duchess of Kent, Elizabeth Taylor, Audrey Hepburn, Gloria Vanderbilt and Jacqueline Kennedy.